Global optimization of cerebral cortex layout

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Global optimization of cerebral cortex layout.

Functional areas of mammalian cerebral cortex seem positioned to minimize costs of their interconnections, down to a best-in-a-billion optimality level. The optimization problem here, originating in microcircuit design, is: Given connections among components, what is the physical placement of the components on a surface that minimizes total length of connections? Because of unfeasibility of mea...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2004

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0305212101